Top MLB DFS Plays & Pick 'Em 5/6 | Tackling Tuesday's MONSTER Slate! ⚾

Tuesday, May 6th ⚾️ DFS Plays & Props for Today's MLB Action

Penned By: @Ryan_Humphries on Twitter/X and LineStar Chat.

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Main Slate Rundown 🏟

As usual, Tuesday will provide us with a doozy of a slate. A dozen games are lined up for this evening’s main slate action! We’ve got a multitude of aces to choose from and plenty of hitters/stacks in advantageous spots. Weather could cause some issues in a couple of games -- most notably, the Coors Field matchup, so stay on top of the latest forecast if you intend to load up on Coors bats (or pitchers). Other than that, it should be another entertaining evening of baseball! Best of luck!

Update: DET at COL has been postponed!

Main slate match-ups with implied run totals and moneyline odds:

Reminder: DET/COL has been PPD.

💣5/6 Dinger Report💣

Main Slate Weather Outlook 💨🌦️☁️

Check LineStar's MLB Daily Dashboard to see an overview of the most up-to-date game forecasts.

  • PHI at TB (7:05 ET, 8.0 O/U): Can’t rule out a stray shower rolling over the ballpark but it’s more likely that this game plays without any problems. Hot temps in the upper 80s at first pitch with 5-10 mph winds, mostly IN from right/center.

  • SD at NYY (7:05 ET, 7.5 O/U): Rain will be in the area but is currently looking like it’s going to hold west of the ballpark. Just keep an eye on things here in case anything changes. Temps around 60 degrees with light winds IN from right.

  • DET at COL (8:40 ET, 9.5 O/U): As touched on in the intro, this is the main trouble spot today. Rain is pretty much a guarantee throughout the afternoon and into the evening. How late it lingers is still TBD but there is a likely chance of some sort of delay, and a postponement is firmly on the table. If they do manage to get this game in, temps will be in the 40s with swirling 5-10 mph winds.

    Update: DET/COL has been postponed.

  • TOR at LAA (9:38 ET, 9.0 O/U): 5-10 mph winds OUT to left.

  • NYM at ARI (9:40 ET, 9.0 O/U): The roof at Chase Field is scheduled to be open this evening. It’s not particularly warm in Phoenix today but the bats receive a slight bump nonetheless.

  • SEA at ATH (10:05 ET, 10.0 O/U): Near 80 degrees at first pitch with 10-15 mph winds OUT to left. Nice spot for hitters.

Pitchers to Consider ⚾

Zack Wheeler (RHP), PHI | DK: $9.7k, FD: $11k | at TB

We have a handful of top-flight arms to choose from today but we’ll begin with Zack Wheeler. Wheeler has had a couple of lackluster outings already this season, which is uncharacteristic for arguably the most reliable starting pitcher in the game. That said, he does own a slate-best 2.48 xERA and 2.66 xFIP to go along with a flat 1.00 WHIP and a slate-leading 32.8% kRate. Wheeler is 5th among MLB starting pitchers (min. 30 IP) with a 116 Pitching+ rating, so his stuff and his location have been on point.

Wheeler will draw a matchup with a Rays offense that hasn’t been in the best form lately. Against RHPs L2Weeks, the Rays are 23rd in OPS, 24th in wOBA, 26th in ISO, 19th in wRC+, and they’ve struck out at a 26.0% clip (2nd highest). Wheeler has cleared at least six innings in six of his seven starts this season so he’s always a great bet to pitch deep into the game and he should come away with a sizable strikeout total today as well.

 

Chris Sale (LHP), ATL | DK: $8.8k, FD: $9.9k | vs. CIN

After a slow start to the season, we’re still getting a nice discount on Sale, at least on DraftKings where he could certainly outperform his $8,800 price point. Sale has been a bit unlucky this season as both his 3.32 xERA and 3.26 xFIP are over a run-and-a-half lower than his 4.84 ERA. He is still getting strikeouts with an excellent 29.3% kRate/14.0% SwStr%. And Sale is coming off of easily his best outing of the season, which happened to be a Coors Field start where he covered seven innings on 100 pitches, allowing just two runs while striking out 10 batters. Sale’s most used pitch, his slider (45.8% USG%), has generated a huge 44.7% Whiff% and opponents are hitting just .176 against that pitch.

The Reds were nearly no-hit yesterday so their bats will be motivated to bounce back today. For the most part, they’ve been a very average/below-average offense against lefty pitchers this season. They’ve hit for just a .223 AVG (ranks 20th) with a .692 OPS (14th), and 91 wRC+ (14th) with a 22.6% kRate. So it’s not an ideal matchup but it is certainly a spot where Sale can succeed. The Braves (-225 ML) are also the second-heaviest favorites on the evening.

 

Matthew Liberatore (LHP), STL | DK: $8.2k, FD: $9k | vs. PIT

It’s not the best slate for value pitching so we aren’t going too cheap for our final spotlighted pitcher. Liberatore has had a fairly strong campaign thus far in 2025, pitching to a 3.44 ERA, 2.91 xFIP, 0.97 WHIP, and 22.6% kRate. Liberatore has also walked just three batters all season, resulting in a slate-best 2.3% BB%. Were it not for a lengthy rain delay that shortened his last start to just three innings, Liberatore likely would have cleared at least 6.0 IP in all six of his starts this season. Liberatore also tends to be at his best at home, where he averages +43.0% more FPPG.

Liberatore draws a plus matchup with a Pirates team that is bottom 10 against lefties in OPS, wOBA, ISO, wRC+, and strikeout rate (25.3%). In 62 plate appearances versus the current Pittsburgh roster, Liberatore has held them to a .186 AVG and .242 wOBA while racking up a 25.8% kRate. The Pirates are rolling out their ace, Paul Skenes, today so pitching himself into a winning position will be a bit more difficult than usual, but it remains a strong all-around spot for Liberatore.

 

Other Pitchers to Consider

Paul Skenes (RHP), PIT | DK: $10k, FD: $10.8k | at STL

Pablo Lopez (RHP), MIN | DK: $9k, FD: $9.5k | vs. BAL

Seth Lugo (RHP), KC | DK: $8.7k, FD: $9.2k | vs. CWS

Colin Rea (RHP), CHC | DK: $7.3k, FD: $7.6k | vs. SF

Team Stacks to Target 🎯

Disclaimer: Stacking in MLB DFS is not a requirement but it is a very common strategy used to take down GPPs. This strategy is covered in more detail in the MLB DFS strategy guide linked in the header at the top of this newsletter. Check out the MLB StackFinder on LineStar.

Athletics vs. Emerson Hancock (RHP), SEA

As noted in the weather section, conditions at Sutter Health Park (#2 most hitter-friendly ballpark) are perhaps the most hitter-friendly on the slate with warm temps near 80 degrees at first pitch and 10-15 mph winds blowing out to left. And, to no surprise, we’re seeing a slate-high 10.0 over/under being pinned on this game. So, we’re expecting plenty of scoring in this nightcap game and the A’s hitters land in a prime spot. Emerson Hancock has acquired an ugly 6.62 ERA and 1.75 WHIP across his four starts and he has mustered just an 18.8% kRate with a 7.9% SwStr%. And he has struggled against both sides of the plate, allowing a .400 wOBA to LHBs and a .392 wOBA to RHBs. The A’s themselves have been a solid offense, ranking 10th with a 118 wRC+ vs. RHPs L2Weeks. Seattle’s bullpen is also going to be thin on options tonight as they were forced to use five relievers in yesterday’s extra innings game after starter Bryce Miller managed to clear just four innings on 94 pitches. Four of the five Mariners relievers used yesterday threw at least 22 pitches.

Favorite ATH Bats: Brent Rooker, Lawrence Butler, Shea Langeliers

Bargain Bat: Miguel Andujar

 

Minnesota Twins vs. Cade Povich (LHP), BAL

The Twins have been among the more frustrating offenses to figure out this season, for me anyway, but they set up nicely at home this evening. The Twins have been stout against lefty pitching and, against LHPs L2Weeks (102 PA), they’re batting .333 with an .869 OPS, .384 wOBA, 153 wRC+, and a low 15.7% kRate. A case can be made that Cade Povich is the lowest-quality starter on this slate as he brings a 5.16 ERA, 6.10 xERA, 1.65 WHIP, and 15.0% HR/FB Rate into his seventh start of the season. Povich has also allowed 10 barreled balls over the last 30 days (bottom 5th percentile) and an average exit velo of 91.4 mph (bottom 15th percentile). The Twins have a very righty-heavy lineup that they’re throwing at Povich today with eight RHBs in the order. Povich has had traditional splits and has been MUCH worse against RHBs, allowing a .442 wOBA, .269 ISO, and 2.49 HR/9 Rate to that side of the plate. Another nice bonus about stacking teams against the O’s is the chance to get some innings versus their struggling bullpen. Over the last two weeks, the Orioles bullpen has allowed a .305 AVG with a 6.05 ERA, 1.66 WHIP, and 2.38 HR/9 Rate. Minnesota is also getting a big piece to their lineup back today as Royce Lewis is making his season debut (though, he did not put up good numbers during his rehab assignment). By all indications, the Twins should string together some big hits and homers today.

Favorite MIN Bats: Byron Buxton, Ryan Jeffers, Royce Lewis

Bargain Bat: Carlos Correa

Low-Owned Stack That Just Might Work Out 🤔

San Diego Padres vs. Clarke Schmidt (RHP), NYY

Every hitter in the projected Padres lineup has a <10% pOwn% with eight hitters landing in under 5% pOwn%. Clarke Schmidt can be a serviceable pitcher at times but there is nothing special about his 5.52 ERA and 4.81 xFIP so far this season. The Padres bats have struggled versus RHPs in recent weeks, but they are getting back to full strength and are adding a massive piece to the lineup, Jackson Merrill, back into the mix today. Merrill hasn’t played since April 6th due to a hamstring injury but, when he was in the lineup over the first 10 games of the season, the Padres were a top-10 offense and boasted a .354 wOBA and 128 wRC+ vs. RHPs. The Yankees do have a quality bullpen to deploy behind Schmidt but there is still plenty of hope that the Padres can do some damage today. Yankee Stadium has been the #4 most hitter-friendly ballpark this season, and the #1 home run ballpark. I’ll be expecting San Diego to outperform their 3.6 implied run total today.

Favorite SD Bats: Jackson Merrill, Fernando Tatis Jr., Manny Machado

Bargain Bat: Luis Arraez

One-Off Bats ☝️

A maximum of one hitter per team will be listed below. Feel free to use these players as one-off options, one-half of a two-man mini-stack, or a core piece to a full team stack.

OF Aaron Judge, NYY vs. Michael King (RHP), SD

OF Kyle Tucker, CHC vs. Justin Verlander (RHP), SF

SS Elly De La Cruz, CIN vs. Chris Sale (LHP), ATL

SS Bobby Witt Jr., KC vs. Sean Burke (RHP), CWS

OF Brent Rooker, ATH vs. Emerson Hancock (RHP), SEA

2B Ketel Marte, ARI vs. David Peterson (LHP), NYM

OF Jackson Merrill, SD vs. Clarke Schmidt (RHP), NYY

OF Kyle Schwarber, PHI vs. Drew Rasmussen (RHP), TB

SS Francisco Lindor, NYM vs. Zac Gallen (RHP), ARI

1B Vlad Guerrero Jr., TOR vs. Tyler Anderson (LHP), LAA

OF Byron Buxton, MIN vs. Cade Povich (LHP), BAL

3B Austin Riley, ATL vs. Andrew Abbott (LHP), CIN

C Cal Raleigh, SEA vs. Jeffrey Springs (LHP), ATH

OF Mike Yastrzemski, SF vs. Colin Rea (RHP), CHC

1B/OF Ryan O’Hearn, BAL vs. Pablo Lopez (RHP), MIN

OF Christian Yelich, MIL vs. Hayden Wesneski (RHP), HOU

SS Zach Neto, LAA vs. Jose Urena (RHP), TOR

SS Jeremy Pena, HOU vs. Chad Patrick (RHP), MIL

Bargain Bats 💸

Note: Additional hitting value may open up once all official starting lineups are released. For now, here are some cheap hitters who are already confirmed or currently expected to be on the field tonight and find themselves in a good spot to pay off their modest DFS salaries.

1B Luis Arraez, SD vs. Clarke Schmidt (RHP), NYY

3B Maikel Garcia, KC vs. Sean Burke (RHP), CWS

OF Miguel Andujar, ATH vs. Emerson Hancock (RHP), SEA

OF Bryan Reynolds, PIT vs. Matthew Liberatore (LHP), STL 

C Ryan Jeffers, MIN vs. Cade Povich (LHP), BAL

SS JP Crawford, SEA vs. Jeffrey Springs (LHP), ATH

SS Carlos Correa, MIN vs. Cade Povich (LHP), BAL

1B Vinnie Pasquantino, KC vs. Sean Burke (RHP), CWS

OF Eli White, ATL vs. Andrew Abbott (LHP), CIN

3B/OF Jonathan India, KC vs. Sean Burke (RHP), CWS

C Alejandro Kirk, TOR vs. Tyler Anderson (LHP), LAA

OF Drew Waters, KC vs. Sean Burke (RHP), CWS

2B/SS Chase Meidroth, CWS vs. Seth Lugo (RHP), KC

Home Run Calls of the Day 💣

Make sure you’re following @LineStarApp on Twitter/X. Retweet the Home Run Calls of the Day tweet for your chance to win prizes!

Ryan’s PrizePicks Power Play of the Day

Here is a two-pick “Power Play” I’m liking for today's MLB action over on PrizePicks! Nothing is ever a guarantee to hit but I put my own money on these picks so I don't just lightly throw them out there without believing they'll cash!

Matthew Liberatore MORE than 17.5 Pitching Outs

Freddie Freeman MORE than 1.5 Total Bases

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Best of luck out there today, everyone!

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