MLB Opening Night: Giants vs. Yankees DFS Cheat Sheet! ⚾

Wednesday, March 25th ⚾️ MLB DFS Game Info & Cheat Sheet for Opening Night!

Penned By: @Ryan_Humphries on Twitter/X and LineStar Chat.

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The new MLB season has arrived! The 2026 campaign gets underway with an Opening Night showdown between the Yankees and Giants, a light appetizer before Thursday’s full Opening Day slate and the six-month grind that follows.

Before things really get rolling, we’ve got a single-game showdown slate to work with on Wednesday night. Below is a cheat sheet with some quick thoughts on top captain/MVP options and FLEX plays. As always with early-season MLB, expect a bit more volatility than usual, so keep that in mind with your bankroll approach.

Also, if you missed it, LineStar’s 2026 MLB DFS Primer & Strategy Guide is linked at the top of this newsletter – it is meant to serve either as an introduction to the sport, from a DFS perspective, or just as an all-around refresher for returning DFS vets.

Let’s get into tonight’s showdown. Best of luck!

New York Yankees (-121) at San Francisco Giants | 7.0 O/U

Yankees: 3.6 Implied Runs | Giants: 3.4 Implied Runs

Notable Injuries: NYY SS Anthony Volpe – OUT

Starting Pitchers: Max Fried (LHP), NYY & Logan Webb (RHP), SF

First Pitch & Streaming: 8:05 ET/5:05 PT | Netflix

Ballpark: Oracle Park (16th in Park Factor last season)

Weather: Partly cloudy, mid-60s temps, and 10 mph winds blowing out to center (reminder: Oracle Park’s design mitigates wind impacts)

Note: These are not confirmed lineups.

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